{"id":890,"date":"2018-06-21T11:24:37","date_gmt":"2018-06-21T09:24:37","guid":{"rendered":"https:\/\/hiperinsulinka.pl\/?p=890"},"modified":"2020-06-22T12:39:47","modified_gmt":"2020-06-22T10:39:47","slug":"co-laczy-tkanke-tluszczowa-z-insulinoopornoscia","status":"publish","type":"post","link":"https:\/\/hiperinsulinka.pl\/index.php\/co-laczy-tkanke-tluszczowa-z-insulinoopornoscia\/","title":{"rendered":"Co \u0142\u0105czy tkank\u0119 t\u0142uszczow\u0105 z insulinooporno\u015bci\u0105?"},"content":{"rendered":"

Czy zastanawiali\u015bcie si\u0119 kiedy\u015b jak tkanka t\u0142uszczowa mo\u017ce wp\u0142ywa\u0107 na insulinooporno\u015b\u0107? Czy jej nadmiar w jaki\u015b spos\u00f3b wp\u0142ywa na jej powstawanie i jak obni\u017caj\u0105c ilo\u015b\u0107 tkanki t\u0142uszczowej w organizmie mo\u017cemy poprawi\u0107 parametry glukozy i insuliny?<\/strong><\/p>\n

Insulinooporno\u015b\u0107 jest \u015bci\u015ble zwi\u0105zana z nadwag\u0105 , oty\u0142o\u015bci\u0105 i zawarto\u015bci\u0105 tkanki t\u0142uszczowej w organizmie. Osoby z zaburzeniami gospodarki w\u0119glowodanowej najcz\u0119\u015bciej borykaj\u0105 si\u0119 z oty\u0142o\u015bci\u0105 trzewn\u0105 ( okolice brzucha).<\/p>\n

Dlaczego tkanka t\u0142uszczowa jest\u00a0 kluczowym elementem?<\/span><\/strong><\/span><\/p>\n

Ogniwem , kt\u00f3ry \u0142\u0105czy insulinooporno\u015b\u0107 z tkank\u0105 t\u0142uszczow\u0105 s\u0105 wolne kwasy t\u0142uszczowe<\/strong> (FFA)<\/span>, kt\u00f3rych \u017ar\u00f3d\u0142em jest g\u0142\u00f3wnie tkanka t\u0142uszczowa trzewna (VAT)\u00a0 a w mniejszym stopniu tkanka podsk\u00f3rna (SAT). Ich nadmierna ilo\u015b\u0107 powoduje uwolnienie wolnych kwas\u00f3w t\u0142uszczowych do krwiobiegu.<\/p>\n

Tkanka t\u0142uszczowa( kom\u00f3rki t\u0142uszczowe-\u00a0 adipocyty) to nie tylko nadmiar t\u0142uszczu zgromadzony w ciele ale tak\u017ce pr\u0119\u017cnie dzia\u0142aj\u0105cy narz\u0105d do produkcji r\u00f3\u017cnych hormon\u00f3w, substancji\u00a0 i zwi\u0105zk\u00f3w aktywnych biologicznie wp\u0142ywaj\u0105cych na ca\u0142y organizm w tym na dzia\u0142anie insuliny.<\/p>\n

Jakie substancje produkuje tkanka t\u0142uszczowa:<\/strong><\/h4>\n
    \n
  • Adiponektyna ( zwi\u0119ksza insulinowra\u017cliwo\u015b\u0107)<\/li>\n
  • Leptyna ( hormon hamuj\u0105cy \u0142aknienie)<\/li>\n
  • Interleukiny ( bior\u0105ce udzia\u0142 w stanie zapalnym)<\/li>\n
  • Rezystyna (nasila powstawanie glikogenu w w\u0105trobie)<\/li>\n
  • TNF-\u03b1 ( czynnik martwicy nowotworu- bierze udzia\u0142 w stanie zapalnym)<\/li>\n<\/ul>\n

    U os\u00f3b z nadmiarem tkanki t\u0142uszczowej , nadmierna jest ilo\u015b\u0107 adipocyt\u00f3w ( kom\u00f3rek t\u0142uszczowych), kt\u00f3re w g\u0142\u00f3wnej mierze magazynuj\u0105 zapasy t\u0142uszczu.\u00a0 Oty\u0142o\u015b\u0107 wp\u0142ywa na wzrost i ilo\u015b\u0107 adipocyt\u00f3w w naszym ciele, prze\u0142adowane tkank\u0105 t\u0142uszczow\u0105 adipocyty nie dzia\u0142aj\u0105 ju\u017c sprawnie.<\/strong><\/span><\/h4>\n
      \n
    • Nabieraj\u0105 oporno\u015bci na insulin\u0119 -> nie s\u0105 w stanie reagowa\u0107 na kolejne wyrzuty insuliny<\/li>\n
    • Zmniejszaj\u0105 zdolno\u015b\u0107 do gromadzenia lipid\u00f3w -> lipidy transportowane s\u0105 do innych narz\u0105d\u00f3w do tego nie przystosowanych<\/li>\n
    • Wytwarzaj\u0105 mniejsz\u0105 ilo\u015b\u0107 adipokin -> hormony tkanki t\u0142uszczowej<\/li>\n
    • Wytwarzaj\u0105 wi\u0119ksz\u0105 ilo\u015b\u0107 cytokin prozapalnych ( zwi\u0119kszaj\u0105c stan zapalny i nap\u0119dzaj\u0105 insulinooporno\u015b\u0107)<\/li>\n
    • Zwi\u0119kszaj\u0105 powstawanie reaktywnych form tlenu -> powoduj\u0105c uszkodzenie \u015br\u00f3db\u0142onka naczy\u0144 i stan zapalny<\/li>\n<\/ul>\n
      W\u00a0 krwiobiegu zaczyna kr\u0105\u017cy\u0107 zbyt du\u017co wolnych kwas\u00f3w t\u0142uszczowych, kt\u00f3rych tkanka t\u0142uszczowa ju\u017c nie mog\u0142a przyj\u0105\u0107 ze wzgl\u0119du na obecnie zbyt du\u017ce ob\u0142o\u017cenie lipidami.<\/strong><\/h5>\n

      Takie wolne kwasy t\u0142uszczowe, kt\u00f3re nie mog\u0105 trafi\u0107 w miejsce docelowe jakim jest tkanka t\u0142uszczowa trafiaj\u0105 do narz\u0105d\u00f3w nie przystosowanych do ich przyj\u0119cia czyli : w\u0105troby i mi\u0119\u015bni. W ten spos\u00f3b rozwija si\u0119 insulinooporno\u015b\u0107 w tych narz\u0105dach.<\/strong><\/span><\/p>\n

      W mi\u0119\u015bniach nast\u0119puje zaburzone magazynowanie glukozy w postaci glikogenu. Lipidy wp\u0142ywaj\u0105 na zahamowanie szlaku insulinowego, transportery glukozy i insuliny s\u0105 nieefektywne i w efekcie glukoza nie jest wychwytywana przez mi\u0119\u015bnie i dalej kr\u0105\u017cy we krwi ( cho\u0107 powinna by\u0107 ju\u017c wy\u0142apana przez transportery i przetworzona na energi\u0119).<\/p>\n

      W konsekwencji nadmiar glukozy a tak\u017ce insuliny hamuje proces lipolizy ( czyli rozpadu tkanki t\u0142uszczowej) , to powoduje trudno\u015bci ze schudni\u0119ciem i pozbycia si\u0119 nadmiaru kilogram\u00f3w.<\/strong><\/p>\n

      \"\"<\/p>\n

      Nie jest to \u0142atwe do wyt\u0142umaczenia, w tych procesach bierze udzia\u0142 mn\u00f3stwo hormon\u00f3w, przeka\u017anik\u00f3w i transporter\u00f3w, bia\u0142ek, ale stara\u0142am si\u0119 zobrazowa\u0107 jakie jest powi\u0105zanie mi\u0119dzy nadmiarem tkanki t\u0142uszczowej a rozwojem insulinooporno\u015bci.<\/p>\n

      Tak wiele m\u00f3wi si\u0119, \u017ce utrata masy cia\u0142a i zmniejszenie tkanki t\u0142uszczowej w organizmie jest kluczowym elementem leczenia insulinooporno\u015b\u0107i. Teraz ju\u017c wiadomo dlaczego tak si\u0119 dzieje i jak ten nadmiar wp\u0142ywa na zaburzony metabolizm glukozy i insuliny w organizmie.<\/strong><\/h5>\n

      Udzia\u0142 kwas\u00f3w t\u0142uszczowych i tkanki t\u0142uszczowej w indukowaniu insulinooporno\u015bci mi\u0119\u015bni szkieletowych. Chaci\u0144ska M., Zabielski P., \u00a0Grycel S.,\u00a0B\u0142achnio-Zabielska A.,\u00a0Postepy Hig Med Dosw (online), 2016; 70: 1142-1149<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

      Czy zastanawiali\u015bcie si\u0119 kiedy\u015b jak tkanka t\u0142uszczowa mo\u017ce wp\u0142ywa\u0107 na insulinooporno\u015b\u0107? Czy jej nadmiar w jaki\u015b spos\u00f3b wp\u0142ywa na jej powstawanie i jak obni\u017caj\u0105c ilo\u015b\u0107 tkanki t\u0142uszczowej w organizmie mo\u017cemy poprawi\u0107 parametry glukozy i insuliny? Insulinooporno\u015b\u0107 jest \u015bci\u015ble zwi\u0105zana z nadwag\u0105 , oty\u0142o\u015bci\u0105 i zawarto\u015bci\u0105 tkanki t\u0142uszczowej w organizmie. Osoby z zaburzeniami gospodarki w\u0119glowodanowej najcz\u0119\u015bciej…<\/p>\n","protected":false},"author":2,"featured_media":892,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-890","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"yoast_head":"\nCo \u0142\u0105czy tkank\u0119 t\u0142uszczow\u0105 z insulinooporno\u015bci\u0105? - Hiperinsulinka<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hiperinsulinka.pl\/index.php\/co-laczy-tkanke-tluszczowa-z-insulinoopornoscia\/\" \/>\n<meta property=\"og:locale\" content=\"pl_PL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Co \u0142\u0105czy tkank\u0119 t\u0142uszczow\u0105 z insulinooporno\u015bci\u0105? - Hiperinsulinka\" \/>\n<meta property=\"og:description\" content=\"Czy zastanawiali\u015bcie si\u0119 kiedy\u015b jak tkanka t\u0142uszczowa mo\u017ce wp\u0142ywa\u0107 na insulinooporno\u015b\u0107? 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